Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts that functions as a cytokine
The pharmaceutical analogs of naturally occurring GM-CSF are called sargramostim and molgramostim
Reconstitution It is recommended that sterile ddH2O containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of not less than 1 mg/mL of the cytokine.
Description
Colonies can be formed by stimulating factors or recombinant GM-CSF and CSFs activity expressed in Units compared to a standard.Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation
Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex
NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
Properties
E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies
Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens)
Depending on the epitopes used human ELISA kits can be cross reactive to many other species
Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Sample Types
serum, blood, plasma, saliva, urine, and other related tissue liquid