Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein
OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice
Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models
These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.
Properties
E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies
Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens)
Depending on the epitopes used human ELISA kits can be cross reactive to many other species
Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
About
Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts
There are 2 heavy chains, 2 light chains
The IgG antibody has 2 antigen binding sites
They represent 70% or more of serum antibodies
This antibody can be antigen purified or protein A or G purified
For storage sodium azide is added or you can call us to request azide free antibody preparations
These will need colder storage temperatures.
Sample Types
serum, blood, plasma, saliva, urine, and other related tissue liquid