Human ovalbumin specific IgE,OVA sIgE ELISA Kit

Information

Name

  • Human ovalbumin specific IgE,OVA sIgE ELISA Kit

Size

  • 96T

Catalog No

  • E1392Hu

Price

  • 634 €

Extended details

Properties

  • E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies
  • Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens)
  • Depending on the epitopes used human ELISA kits can be cross reactive to many other species
  • Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.Immunoglobulin E (IgE) kappa or Fc specific antibody is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals
  • IgE is synthesized by plasma cells
  • Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4)
  • IgEs play a role in allergy and response to parasite infection
  • High levels of IgEs caused by parasites can lower the allergic reaction of patients to allergens common present in the human environment
  • As such the parasite history of an allergic patient needs to be taken in consideration as a positive factor.

Gene

  • Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein
  • OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice
  • Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models
  • These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.

Sample Types

  • serum, blood, plasma, saliva, urine, and other related tissue liquid

Test

  • ELISA Enzyme-linked immunosorbent assays Code 90320007 SNOMED

Platform

  • Microplate Reader

Object tested

  • Human

Additional isotype

  • IgE