Thymopoietin I and II are proteins involved in the induction of CD90 in the thymus
The thymopoetin (TMPO) gene encodes three alternatively spliced mRNAs encoding proteins of 75 kDa (alpha), 51 kDa (beta) and 39 kDa (gamma) which are ubiquitously expressed in all cells
The human TMPO gene maps to chromosome band 12q22 and consists of eight exons
TMPO alpha is present diffusely expressed with the cell nucleus while TMPO beta and gamma are localized to the nuclear membrane
TMPO beta is a human homolog of the murine protein LAP2
LAP2 plays a role in the regulation of nuclear architecture by binding lamin B1 and chromosomes
This interaction is regulated by phosphorylation during mitosis
Given the nuclear localization of the three TMPO isoforms, it is unlikely that these proteins play any role in CD90 induction.
Properties
E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies
Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens)
Depending on the epitopes used human ELISA kits can be cross reactive to many other species
Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Sample Types
serum, blood, plasma, saliva, urine, and other related tissue liquid