Thymopoietin I and II are proteins involved in the induction of CD90 in the thymus
The thymopoetin (TMPO) gene encodes three alternatively spliced mRNAs encoding proteins of 75 kDa (alpha), 51 kDa (beta) and 39 kDa (gamma) which are ubiquitously expressed in all cells
The human TMPO gene maps to chromosome band 12q22 and consists of eight exons
TMPO alpha is present diffusely expressed with the cell nucleus while TMPO beta and gamma are localized to the nuclear membrane
TMPO beta is a human homolog of the murine protein LAP2
LAP2 plays a role in the regulation of nuclear architecture by binding lamin B1 and chromosomes
This interaction is regulated by phosphorylation during mitosis
Given the nuclear localization of the three TMPO isoforms, it is unlikely that these proteins play any role in CD90 induction.
Test
ELISA Enzyme-linked immunosorbent assays Code 90320007 SNOMED,Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab
Mouse are mature after 40 days for females and 55 days for males
The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year
Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Properties
E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays,E05 478 566 350 170 or Enzyme-Linked Immunosorbent Assays
Sample Types
serum, blood, plasma, saliva, urine, and other related tissue liquid